Phenoxyacetyl Chloride , >98.0%(GC) , 701-99-5

CAS NO.：701-99-5

Empirical Formula: C8H7ClO2

Molecular Weight: 170.59

MDL number: MFCD00000726

EINECS: 211-862-4

PRODUCT Properties

• Melting point: 100-100.5 °C
• Boiling point: 225-226 °C (lit.)
• Density: 1.235 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.534(lit.)
• Flash point: 227 °F
• storage temp.: Store at RT.
• form: Liquid
• color: Clear slightly yellow to brown
• Water Solubility: Reacts with water.
• Sensitive: Moisture Sensitive
• BRN: 607585
• InChI: InChI=1S/C8H7ClO2/c9-8(10)6-11-7-4-2-1-3-5-7/h1-5H,6H2
• InChIKey: PKUPAJQAJXVUEK-UHFFFAOYSA-N
• SMILES: C(Cl)(COC1=CC=CC=C1)=O
• CAS DataBase Reference: 701-99-5(CAS DataBase Reference)
• NIST Chemistry Reference: Acetyl chloride, phenoxy-(701-99-5)
• EPA Substance Registry System: Acetyl chloride, phenoxy- (701-99-5)

Description and Uses

Phenoxyacetyl chloride was used in the synthesis of:

• series of macrocyclic bis-β-lactams
• 5-phenyl-6-epiphenoxymethylpenicillin benzyl ester
• N-protected guanosine derivatives, useful in RNA synthesis
• phenyloxyketene, for cycloaddition to imines leading to β-lactams

Safety

• Symbol(GHS): GHS05,GHS07
• Signal word: Danger
• Hazard statements: H314-H335
• Precautionary statements: P261-P271-P280-P301+P330+P331-P303+P361+P353-P305+P351+P338
• Hazard Codes: C
• Risk Statements: 14-34-36/37
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• F: 10-19
• TSCA: Yes
• HazardClass: 8
• PackingGroup: II
• HS Code: 29189090
• Limited Quantities: 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)