A6947058
Donepezilhydrochloridemonohydrate , 10mMinDMSO , 120014-06-4
CAS NO.：120014-06-4
Empirical Formula: C24H29NO3
Molecular Weight: 379.49
MDL number: MFCD00912833
EINECS: 601-651-9
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB239.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 207°C |
| Boiling point: | 527.9±50.0 °C(Predicted) |
| Density | 1.141±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Acetone (Slightly), Chloroform (Slightly) |
| form | Solid |
| pka | 8.84±0.10(Predicted) |
| color | White to Off-White |
| Water Solubility | 2.931 mg/L |
| InChI | InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3 |
| InChIKey | ADEBPBSSDYVVLD-UHFFFAOYSA-N |
| SMILES | C1(=O)C2=C(C=C(OC)C(OC)=C2)CC1CC1CCN(CC2=CC=CC=C2)CC1 |
| CAS DataBase Reference | 120014-06-4(CAS DataBase Reference) |
Description and Uses
Donepezil is another “nonclassic,” centrally acting, reversible, noncompetitive AChEI that was approved in 1997 for treatment of mild-to-moderate AD and dementia. Its selectivity for AChE is 570- to 1,250-fold that for butyrylcholinesterase, and it also exhibits greater affinity for brain AChE than for AChE in the periphery.
Donepezil is a cholinesterase inhibitors.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-36/37/39 |
| RIDADR | UN 2811 |
| HS Code | 29333990 |
| Hazardous Substances Data | 120014-06-4(Hazardous Substances Data) |
