Pyrazine-2-amidoxime , 97% , 51285-05-3

CAS NO.：51285-05-3

Empirical Formula: C5H6N4O

Molecular Weight: 138.13

MDL number: MFCD02258397

PRODUCT Properties

• Melting point: 179-182°C
• solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 0.2 mg/ml; PBS (pH 7.2): 0.1 mg/ml
• form: A crystalline solid
• InChI: 1S/C5H6N4O/c6-5(9-10)4-3-7-1-2-8-4/h1-3,10H,(H2,6,9)
• InChIKey: QZHJCRJEMIFNNB-UHFFFAOYSA-N
• SMILES: N\C(=N/O)c1cnccn1

Description and Uses

Pyrazine-2-amidoxime is a synthetic intermediate useful for pharmaceutical synthesis.

Pyrazine-2-amidoxime is a structural analogue of pyrazine-2-carboxamide with antimicrobial activity. Pyrazine-2-amidoxime shows killing and inhibiting properties against Candida albicans, fungal pathogen and Gram-positive bacteria[1].

Safety

• Symbol(GHS): GHS05,GHS06
• Signal word: Danger
• Hazard statements: H301-H315-H318-H335
• Precautionary statements: P280-P301+P310+P330-P302+P352-P305+P351+P338+P310
• target organs: Respiratory system
• Hazard Codes: Xi,T
• Risk Statements: 20/21/22-41-37/38-25
• Safety Statements: 26-36/37/39-45-39
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• HazardClass: IRRITANT
• HS Code: 2933998090
• Storage Class: 6.1C - Combustible acute toxic Cat.3; toxic compounds or compounds which causing chronic effects
• Hazard Classifications: Acute Tox. 3 Oral; Eye Dam. 1; Skin Irrit. 2; STOT SE 3
• Limited Quantities: 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)