PRODUCT Properties
| Melting point: | 225-229 °C |
| alpha | D20 -47°; D27 -42° |
| Boiling point: | 394.4°C (rough estimate) |
| Density | 1.2938 (rough estimate) |
| refractive index | 1.7610 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | Soluble in DMSO (up to 25 mg/ml). |
| form | Powder |
| pka | 13?+-.0.60(Predicted) |
| color | White to Off-white |
| biological source | Cordyceps militaris |
| λmax | 260nm(EtOH)(lit.) |
| Merck | 14,2529 |
| BRN | 35194 |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
| InChIKey | OFEZSBMBBKLLBJ-BAJZRUMYSA-N |
| CAS DataBase Reference | 73-03-0(CAS DataBase Reference) |
| EPA Substance Registry System | Adenosine, 3'-deoxy- (73-03-0) |
Description and Uses
Cordycepin (73-03-0) is an adenosine analog lacking the hydroxyl at the 3’ position. Inhibits PARP1?and polyadenylation2. Displays anti-inflammatory effects1,3?and neuroprotective effects by inhibiting Aβ-induced apoptosis in hippocampal neurons4. Induces apoptosis in a variety of cancer cell lines5. Displays antiobesity effects.6?Inhibits cell senescence via activation of AMPK.7?Maintains stem cell pluripotency and increases iPS cell generation efficiency.8
First reported nucleoside antibiotic.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301+H311+H331 |
| Precautionary statements | P280-P301+P310+P330-P302+P352+P312-P304+P340+P311 |
| Hazard Codes | Xn,T |
| Risk Statements | 40-36/37/38-25-20/21/22 |
| Safety Statements | 22-36-45-26 |
| RIDADR | UN 2811 |
| WGK Germany | 3 |
| RTECS | AU7358610 |
| F | 10-21 |
| HazardClass | 6.1 |
| HS Code | 29349990 |
