A7031158
Chlorambucil , 10mMinDMSO , 305-03-3
Synonym(s):
4-(4-[Bis(2-chloroethyl)amino]phenyl)butyric acid;4-[Bis(2-chloroethyl)amino]benzenebutyric acid;Chlorambucil
CAS NO.：305-03-3
Empirical Formula: C14H19Cl2NO2
Molecular Weight: 304.21
MDL number: MFCD00021783
EINECS: 206-162-0
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 65-70 °C |
| Boiling point: | 460.1±40.0 °C(Predicted) |
| Density | 1.2486 (rough estimate) |
| refractive index | 1.6070 (estimate) |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water, freely soluble in acetone and in ethanol (96 per cent). |
| pka | pKa ～1.3(H2O) (Uncertain) |
| form | Solid |
| color | White to Light yellow |
| Water Solubility | <0.01 g/100 mL at 22 ºC |
| λmax | 588nm(DMSO aq.)(lit.) |
| Merck | 14,2073 |
| BRN | 999011 |
| BCS Class | 3/1 |
| Stability: | Stable, but may be light sensitive. Store cold. Incompatible with strong oxidizing agents. |
| InChIKey | JCKYGMPEJWAADB-UHFFFAOYSA-N |
| CAS DataBase Reference | 305-03-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Chlorambucil(305-03-3) |
| IARC | 1 (Vol. 26, Sup 7, 100A) 2012 |
| EPA Substance Registry System | Chlorambucil (305-03-3) |
Description and Uses
Chlorambucil, approved by the Food and Drug Administration (FDA) in 1957, is an antineoplastic/alkylating agent with a broad spectrum of antitumor activity used to treat chronic lymphocytic leukemia (CLL), Hodgkin’s and non-Hodgkin’s lymphomas.
tranquilization aid
Safety
| Symbol(GHS) |   GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H301-H315-H319-H335-H350 |
| Precautionary statements | P201-P202-P261-P301+P310-P302+P352-P305+P351+P338 |
| Hazard Codes | T |
| Risk Statements | 45-25-36/37/38 |
| Safety Statements | 53-26-45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | ES7525000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29224999 |
| Hazardous Substances Data | 305-03-3(Hazardous Substances Data) |
| Toxicity | LD50 i.p. in rats: 58.2 mmole/kg (Ross) |
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
