A7063758
5-Chloro-8-hydroxy-7-iodoquinoline , 10mMinDMSO , 130-26-7
Synonym(s):
5-Chloro-7-iodo-8-hydroxyquinoline;5-Chloro-7-iodo-8-quinolinol;5-Chloro-8-hydroxy-7-iodoquinoline;Clioquinol;Iodochlorhydroxyquin
CAS NO.：130-26-7
Empirical Formula: C9H5ClINO
Molecular Weight: 305.5
MDL number: MFCD00006787
EINECS: 204-984-4
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 175-183 °C |
| Boiling point: | 350.4±37.0 °C(Predicted) |
| Density | 1.8959 (estimate) |
| vapor pressure | 0Pa at 25℃ |
| storage temp. | 2-8°C |
| solubility | Soluble in DMSO (>25 mg/ml), boiling alcohol ((1:43)), methanol, and chloroform ((1:120)). |
| pka | pKa 8.12(50%aqEtOH t=35.0±0.1 I=0.00 N2atmosphere)(Approximate) |
| form | Solid |
| color | Light Beige to Beige |
| Water Solubility | <0.1 g/100 mL at 20 ºC |
| Merck | 14,5031 |
| BRN | 153637 |
| Major Application | forensics and toxicology pharmaceutical (small molecule) |
| InChI | 1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H |
| InChIKey | QCDFBFJGMNKBDO-UHFFFAOYSA-N |
| SMILES | Oc1c(I)cc(Cl)c2cccnc12 |
| LogP | 1.523 at 24℃ |
| CAS DataBase Reference | 130-26-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 5-Chloro-7-iodo-8-quinolinol(130-26-7) |
| EPA Substance Registry System | Clioquinol (130-26-7) |
Description and Uses
Clioquinol is used as an anti-infective agent; antiamoebic agent; intravaginal trichomonacide; used to impregnate cotton bandages for antibacterial purposes; in animals as an intestinal anti-infective agent.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301-H315-H317-H319 |
| Precautionary statements | P261-P264-P280-P301+P310-P302+P352-P305+P351+P338 |
| PPE | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 36/37/39-45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | VC5075000 |
| TSCA | TSCA listed |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 2933492250 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral Eye Irrit. 2 Skin Irrit. 2 Skin Sens. 1 |
| Hazardous Substances Data | 130-26-7(Hazardous Substances Data) |
| Toxicity | LD50 orally in cats: 400 mg/kg (Davis) |
