<i>S</i>-(2-Aminoethyl)isothiouronium Bromide Hydrobromide , >98.0%(T) , 56-10-0

Synonym(s):
2-(2-Aminoethyl)-2-thiopseudourea dihydrobromide;AET;S-(2-Aminoethyl)isothiouronium bromide hydrobromide;S-(2-Aminoethyl)thiouronium bromide hydrobromide

CAS NO.：56-10-0

Empirical Formula: C3H11Br2N3S

Molecular Weight: 281.01

MDL number: MFCD00037011

EINECS: 200-257-0

PRODUCT Properties

• Melting point: 190-196 °C(lit.)
• Density: 1.94 g/cm3
• storage temp.: Store below +30°C.
• solubility: 50g/l
• form: powder to crystal
• color: White to Almost white
• Water Solubility: almost transparency
• Merck: 14,178
• BRN: 3911163
• InChI: InChI=1S/C3H9N3S.2BrH/c4-1-2-7-3(5)6;;/h1-2,4H2,(H3,5,6);2*1H
• InChIKey: XDVMCVGTDUKDHL-UHFFFAOYSA-N
• SMILES: S(CCN)C(=N)N.Br.Br
• CAS DataBase Reference: 56-10-0(CAS DataBase Reference)
• EPA Substance Registry System: Carbamimidothioic acid, 2-aminoethyl ester, dihydrobromide (56-10-0)

Description and Uses

S-(2-aminoethyl) Isothiourea is a non-selective inhibitor of all NOS isoforms. For human nNOS, eNOS, and iNOS, the K_i values are 1.8, 2.1, and 0.59 μM, respectively.

NOS inhibitor

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
• Hazard Codes: Xn
• Risk Statements: 22-36/37/38
• Safety Statements: 26-36/37-22
• WGK Germany: 3
• RTECS: UM0175000
• F: 10-21
• TSCA: Yes
• HS Code: 2930 90 98
• Toxicity: LD50 in mice (mg/kg): 100 i.v., 280 s.c., 480 i.p., 1600 orally (Pospisil)