A7736958
LicochalconeA , 10mMinDMSO , 58749-22-7
Synonym(s):
(E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one;(E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one;4′,4-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone;Licochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem
CAS NO.：58749-22-7
Empirical Formula: C21H22O4
Molecular Weight: 338.4
MDL number: MFCD01417903
EINECS: 635-678-2
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB311.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 100° |
| Boiling point: | 532.6±50.0 °C(Predicted) |
| Density | 1.171±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMF:25.0(Max Conc. mg/mL);73.88(Max Conc. mM) DMSO:37.67(Max Conc. mg/mL);111.31(Max Conc. mM) Ethanol:43.5(Max Conc. mg/mL);128.54(Max Conc. mM) |
| pka | 7.82±0.15(Predicted) |
| form | Yellow solid |
| color | Yellow-orange |
| BRN | 4534154 |
| InChI | InChI=1S/C21H22O4/c1-5-21(2,3)17-12-15(20(25-4)13-19(17)24)8-11-18(23)14-6-9-16(22)10-7-14/h5-13,22,24H,1H2,2-4H3/b11-8+ |
| InChIKey | KAZSKMJFUPEHHW-DHZHZOJOSA-N |
| SMILES | C(C1=CC=C(O)C=C1)(=O)/C=C/C1=CC(C(C)(C)C=C)=C(O)C=C1OC |
Description and Uses
Licochalcone A is an estrogenic flavonoid that induces apoptosis in multiple types of cancer cells. Licochalcone A applied to bone marrow mesenchymal stem cells (BMSC)-aggregate has strong osteogenetic differentiation thus providing a promising strategy in treating osteoporotic weight-bearing bone fractures with defects.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302+H312+H332 |
| Precautionary statements | P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22 |
| Safety Statements | 36/37 |
| WGK Germany | 3 |
| RTECS | UB8755000 |
