Tangeretin , 95% , 481-53-8

Synonym(s):
4′,5,6,7,8-Pentamethoxyflavone;5,6,7,8-Tetramethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one;NSC 53909;NSC 618905;Ponkanetin

CAS NO.：481-53-8

Empirical Formula: C20H20O7

Molecular Weight: 372.37

MDL number: MFCD00017438

EINECS: 207-570-1

PRODUCT Properties

• Melting point: 153.0 to 157.0 °C
• Boiling point: 565.3±50.0 °C(Predicted)
• Density: 1.244±0.06 g/cm3(Predicted)
• storage temp.: Sealed in dry,Room Temperature
• solubility: DMSO : 25 mg/mL (67.14 mM; Need ultrasonic)
• form: Solid
• color: White to Almost white
• BRN: 351695
• InChI: InChI=1S/C20H20O7/c1-22-12-8-6-11(7-9-12)14-10-13(21)15-16(23-2)18(24-3)20(26-5)19(25-4)17(15)27-14/h6-10H,1-5H3
• InChIKey: ULSUXBXHSYSGDT-UHFFFAOYSA-N
• SMILES: C1(C2=CC=C(OC)C=C2)OC2=C(OC)C(OC)=C(OC)C(OC)=C2C(=O)C=1
• LogP: 1.788 (est)
• CAS DataBase Reference: 481-53-8(CAS DataBase Reference)
• NIST Chemistry Reference: Tangeretin(481-53-8)

Description and Uses

Tangeretin has been used as an antioxidant and antifungal agent to test its effects on ferroptosis inhibition, conidial development, and appressorium formation against Magnaporthe oryzae. It has also been used as a co-chemotherapeutics agent to study its cytotoxic effects in combination with 5-Fluorouracil (5-Fu) on WiDr colon cancer cells.

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H300
• Precautionary statements: P264-P301+P310
• Hazard Codes: T,Xi
• Risk Statements: 25-36/37/38
• Safety Statements: 45-36-26
• RIDADR: UN 2811
• WGK Germany: 3
• RTECS: DJ3102725
• HS Code: 29329990
• Toxicity: rat,LD50,intraperitoneal,> 1gm/kg (1000mg/kg),Advances in Teratology. Vol. 3, Pg. 181, 1968.