Trazodone HCl , 98% , 25332-39-2

Synonym(s):
2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one hydrochloride;Trazodone hydrochloride

CAS NO.：25332-39-2

Empirical Formula: C19H23Cl2N5O

Molecular Weight: 408.32

MDL number: MFCD00079603

EINECS: 246-855-5

PRODUCT Properties

• Melting point: 223-226?C
• Flash point: 9℃
• storage temp.: 2-8°C
• solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 23.3 mg/mL
• form: powder
• color: off-white
• PH: pH (10g/l, 25℃) : 3.9～4.5
• Water Solubility: Soluble at 25mg/ml in methanol. Also soluble in 0.1M HCl or DMSO. Insoluble in water /n
• InChI: InChI=1S/C19H22ClN5O.ClH/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25;/h1-3,5-7,9,15H,4,8,10-14H2;1H
• InChIKey: OHHDIOKRWWOXMT-UHFFFAOYSA-N
• SMILES: O=C1N2C(C=CC=C2)=NN1CCCN1CCN(C2=CC(Cl)=CC=C2)CC1.[H]Cl
• CAS DataBase Reference: 25332-39-2(CAS DataBase Reference)

Description and Uses

A serotonin uptake inhibitor

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Warning
• Hazard statements: H302-H351
• Precautionary statements: P280-P301+P312+P330
• Hazard Codes: Xn,Xi,T,F
• Risk Statements: 22-40-36/37/38-39/23/24/25-23/24/25-11
• Safety Statements: 22-36-37/39-26-45-36/37-16-7
• RIDADR: 3249
• WGK Germany: 3
• RTECS: XZ5660000
• HazardClass: 6.1(b)
• PackingGroup: III
• HS Code: 29335990
• Toxicity: LD50 i.v. in mice: 96 mg/kg (Silvestrini, Quadri)