Triethyl 2-fluoro-2-phosphonoacetate , ≥96% , 2356-16-3

Synonym(s):
2-Fluoro-2-phosphonoacetic acid triethyl ester;Diethyl [(ethoxycarbonyl)fluoromethyl]phosphonate;Ethyl diethylphosphonofluoroacetate

CAS NO.：2356-16-3

Empirical Formula: C8H16FO5P

Molecular Weight: 242.18

MDL number: MFCD00134400

EINECS: 627-648-2

PRODUCT Properties

• Boiling point: 75 °C0.01 mm Hg(lit.)
• Density: 1.194 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.425(lit.)
• Flash point: 165 °F
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• form: clear liquid
• color: Colorless to Almost colorless
• Specific Gravity: 1.194
• BRN: 1912161
• InChI: InChI=1S/C8H16FO5P/c1-4-12-8(10)7(9)15(11,13-5-2)14-6-3/h7H,4-6H2,1-3H3
• InChIKey: FVPISMANESAJQZ-UHFFFAOYSA-N
• SMILES: C(OCC)(=O)C(P(OCC)(OCC)=O)F
• CAS DataBase Reference: 2356-16-3(CAS DataBase Reference)

Description and Uses

Reactant for:

• Diels-Alder reactions
• Biosynthesis of terpene
• Stereoselective synthesis of unsaturated esters, fluorides and nitriles from the reactions of aldehydes and ketones using Wadsworth-Emmons phosphonates
• Synthesis of quinolones
• Horner-Wadsworth-Emmons asymmetric hydration
• Addition reactions and the subsequent application to click chemistry
• Asymmetric intermolecular Stetter reactions

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H227-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338-P210e-P280a-P405-P501a
• Hazard Codes: Xi,F
• Risk Statements: 36/37/38
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• F: 10-21
• Hazard Note: Irritant
• HazardClass: IRRITANT, FLAMMABLE
• HS Code: 29319090