<i>trans</i>-4-Aminocyclohexanol , >98.0%(GC) , 27489-62-9

CAS NO.：27489-62-9

Empirical Formula: C6H13NO

Molecular Weight: 115.17

MDL number: MFCD00067698

EINECS: 248-492-8

PRODUCT Properties

• Melting point: 108-113°C
• Boiling point: 127 °C / 14mmHg
• Density: 0.9837 (rough estimate)
• refractive index: 1.4713 (estimate)
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: Crystals
• pka: 15.12±0.40(Predicted)
• color: White to almost white
• Water Solubility: Soluble in water.
• Sensitive: Hygroscopic
• InChI: InChI=1S/C6H13NO/c7-5-1-3-6(8)4-2-5/h5-6,8H,1-4,7H2/t5-,6-
• InChIKey: IMLXLGZJLAOKJN-IZLXSQMJSA-N
• SMILES: [C@@H]1(O)CC[C@@H](N)CC1
• LogP: -0.4
• CAS DataBase Reference: 27489-62-9(CAS DataBase Reference)

Description and Uses

trans-4-Aminocyclohexanol is used as raw material in organic synthesis and is an important intermediate in the synthesis of drugs such as Ambroxol hydrochloride. It can react with butyric acid-(2-chloro-ethyl ester) to get butyric acid 4-amino-cyclohexyl ester. This reaction needs catalytic agent Aspergillus niger lipase and solvent 2-methyl-butan-2-ol.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H314-H318
• Precautionary statements: P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P405-P501-P260h-P301+P330+P331-P303+P361+P353-P305+P351+P338-P501a
• Hazard Codes: Xi,C,Xn
• Risk Statements: 36/37/38-34-41-37/38-22
• Safety Statements: 26-37/39-45-36/37/39-39
• RIDADR: 3259
• Hazard Note: Irritant
• HazardClass: 8
• PackingGroup: Ⅲ
• HS Code: 29221990
• Limited Quantities: 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)