BD0433848
Rosiglitazonesodium , 95+% , 316371-83-2
CAS NO.：316371-83-2
Empirical Formula: C18H18N3NaO3S
Molecular Weight: 379.409
MDL number: MFCD09751028
| Pack Size | Price | Stock | Quantity |
| 25g | RMB1808.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| storage temp. | Sealed in dry,Room Temperature |
| InChI | InChI=1S/C18H19N3O3S.Na/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15;/h2-9,15H,10-12H2,1H3,(H,20,22,23);/q;+1/p-1 |
| InChIKey | XFOHHIYSRDUSCX-UHFFFAOYSA-M |
| SMILES | N1([Na])C(=O)C(CC2C=CC(=CC=2)OCCN(C)C2=CC=CC=N2)SC1=O |
Description and Uses
Rosiglitazone sodium is a potent and selective activator of PPARγ, with EC50s of 30 nM, 100 nM and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively, and a Kd of appr 40 nM for PPARγ; Rosiglitazone sodium is also an modulator of TRP channels, inhibits TRP melastatin 2 (TRPM2), TRPM3 and activates TRP canonical 5 (TRPC5).
