BD1530132
4-Chloro-7-fluoro-6-nitroquinazoline , 98% , 162012-70-6
CAS NO.：162012-70-6
Empirical Formula: C8H3ClFN3O2
Molecular Weight: 227.58
MDL number: MFCD08063159
| Pack Size | Price | Stock | Quantity |
| 1g | RMB992.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 395℃ |
| Density | 1.649 |
| Flash point: | 193℃ |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| form | solid |
| pka | 0.53±0.70(Predicted) |
| Appearance | Off-white to light yellow Solid |
| InChI | InChI=1S/C8H3ClFN3O2/c9-8-4-1-7(13(14)15)5(10)2-6(4)11-3-12-8/h1-3H |
| InChIKey | UYQMNEZWVKRWMS-UHFFFAOYSA-N |
| SMILES | N1=C2C(C=C([N+]([O-])=O)C(F)=C2)=C(Cl)N=C1 |
Description and Uses
4-Chloro-7-fluoro-6-nitroquinazoline is an intermediate in the synthesis of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
