1,4,5,6,8-Pentaazaacenaphthylen-3-amine,1,5-dihydro-5-methyl-1-beta-D-ribofuranosyl- , 98+% , 35943-35-2

Synonym(s):
TCN;API-2;MIHC;MYHL;MYO1A

CAS NO.：35943-35-2

Empirical Formula: C13H16N6O4

Molecular Weight: 320.3

MDL number: MFCD00932413

PRODUCT Properties

• Melting point: 207 °C (decomp)
• Boiling point: 459.21°C (rough estimate)
• Density: 1.2633 (rough estimate)
• refractive index: 1.7000 (estimate)
• storage temp.: Store at RT
• solubility: DMSO: >10mg/mL
• form: powder
• pka: 12.35±0.70(Predicted)
• color: tan
• biological source: rabbit
• InChI: InChI=1/C13H16N6O4/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(22)8(21)6(3-20)23-13/h2,4,6,8-9,13,20-22H,3H2,1H3,(H2,14,17)/t6-,8-,9-,13-/s3
• InChIKey: HOGVTUZUJGHKPL-HTVVRFAVSA-N
• SMILES: C12C3=NC=NC=1N(C=C2C(N)=NN3C)[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 |&1:14,15,17,19,r|

Description and Uses

Triciribine hydrate has been used to study the effect of diethyldithiocarbamate (DDC) on matrix metalloproteinase-1 (MMP-1) in hepatic stellate cells¹. It has also been used to analyze ADAM 10 activation by (-)-epigallocatechin-3-gallate (EGCG) in N2a cells overexpressing Swedish mutant APP (SweAPP N2a cells)².

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H317-H319
• Precautionary statements: P280-P305+P351+P338
• WGK Germany: 3
• RTECS: RY8455000