Phenylcarbamate , 95% , 622-46-8
CAS NO.：622-46-8
Empirical Formula: C7H7NO2
Molecular Weight: 137.14
MDL number: MFCD00007961
EINECS: 210-737-1
| Pack Size | Price | Stock | Quantity |
| 1g | RMB60.80 | In Stock |
|
| 5g | RMB219.20 | In Stock |
|
| 10g | RMB382.40 | In Stock |
|
| 25g | RMB744.80 | In Stock |
|
| 100g | RMB2231.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 149-152 °C(lit.) |
| Boiling point: | 251.96°C (rough estimate) |
| Density | 1.2528 (rough estimate) |
| refractive index | 1.5030 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 12.33±0.50(Predicted) |
| form | powder |
| Appearance | White to off-white Solid |
| Water Solubility | Soluble in water. |
| BRN | 2042627 |
| CAS DataBase Reference | 622-46-8(CAS DataBase Reference) |
Description and Uses
Phenyl carbamate is used as various phenyl carbamate esters derived from amino acids, a dipeptide and amino acid esters and amides were prepared and assessed as potential prodrugs with the aim of protecting phenolic drugs against first-pass metabolism following per oral administration.
A tin-catalyzed transcarbamoylation of primary and secondary alcohols with phenyl carbamate proceeds smoothly in toluene at 90℃ to generate the corresponding carbamates in good yields. This mild method exhibits a broad functional-group tolerance.
Y. Ichikawa, Y. Morishita, S. Kusaba, N. Sakiyama, Y. Matsuda, K. Nakano, H. Kotsuki, Synlett, 2010, 1815-1818.
http://dx.doi.org/10.1055/s-0030-1258102
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319-H335-H315 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29242998 |
