Home Categories Chemical Reagents Ethyl2-(diethoxyphosphoryl)butanoate
BD3696648

Ethyl2-(diethoxyphosphoryl)butanoate , 98% , 17145-91-4

Synonym(s):
α-Diethylphosphonobutanoic acid ethyl ester;Ethyl 2-(diethoxyphosphoryl)butanoate;NSC 22423

CAS NO.:17145-91-4

Empirical Formula: C10H21O5P

Molecular Weight: 252.24

MDL number: MFCD00041347

Pack Size Price Stock Quantity
1g RMB68.80 In Stock
5g RMB232.80 In Stock
25g RMB790.40 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Boiling point: 152-154 °C14 mm Hg(lit.)
Density  1.064 g/mL at 25 °C(lit.)
refractive index  n20/D 1.432(lit.)
Flash point: >230 °F
storage temp.  Sealed in dry,Room Temperature
form  Liquid
Specific Gravity 1.064
color  Clear colorless
Water Solubility  Not miscible or difficult to mix with water.
BRN  1789280
InChI InChI=1S/C10H21O5P/c1-5-9(10(11)13-6-2)16(12,14-7-3)15-8-4/h9H,5-8H2,1-4H3
InChIKey GYUCVQSNZFRDRL-UHFFFAOYSA-N
SMILES C(OCC)(=O)C(P(OCC)(OCC)=O)CC

Description and Uses

Reactant for preparation of:

  • Furospinosulin-1 and analogs as hypoxia-selective antitumor agents
  • Aminoquinolines as beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors and potential anti-Alzheimer′s drugs
  • Phenylpropanoic acid peroxisome proliferator-activated receptor (PPAR) α-selective agonists as nonalcoholic steatohepatitis (NASH)-preventive agents
  • PPAR agonists with phenethylphenylphthalimide skeleton derived from thalidomide-related LXR antagonists
  • Notch-sparing γ-secretase inhibitors derived from PPAR agonist library
  • Plakotenin via Diels-Alder reaction, as a potential anticancer agent, naturally found in Okinawan sponge of the genus Plakortis
  • Quinone/naphthoquinone-substituted propenoic acids as inhibitors of cell growth and redox function of apurinic/apyrimidinic endonuclease 1/redox enhancing factor 1 (Ape1/Ref-1)
  • α-alkenyl cyclic ethers by asymmetric dehydrative cyclization of ω-hydroxy allyl alcohols catalyzed by Ru complexes of axially chiral naphthylpyridinecarboxylates
  • Branched phosphonoethoxyethyl purines as new acyclic nucleoside phosphonates which inhibit Plasmodium falciparum (malarial parasite) hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT)
  • Phenylpropanoic acid-type peroxisome proliferator-activated receptor pan agonists as candidate drugs for treatment of altered metabolic homeostasis

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  29310099

RELATED PRODUCTS