BD6269148
3-Deazaadenosine , 99+% , 6736-58-9
Synonym(s):
4-Amino-1-(β-D -ribofuranosyl)-1H-imidazo(4,5)-pyridine
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB721.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 228-229°C |
| Boiling point: | 665.7±65.0 °C(Predicted) |
| Density | 1.90±0.1 g/cm3 (20 ºC 760 Torr) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | H2O: 10 mg/mL with heating to 60 °C |
| form | Solid |
| pka | 13.24±0.70(Predicted) |
| color | White to Off-White |
Description and Uses
3-Deazaadenosine (3-DZA) is an inhibitor of SAH (Sadenosylhomocysteine) hydrolase (Ki = 3.9 μM). It has antiinflammatory properties, inhibiting leukocyte adhesion and chemotaxis, lymphocyte-mediated cytolysis, phagocytosis, degranulation, and NF-κB signaling. 3-DZA also has anti-viral and anti-bacterial activities.
Possesses antiviral activity. It is an inhibitor of leukocyte adhesion to TNF-treated endothelial cells.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H302+H312-H315-H319-H331-H335 |
| Precautionary statements | P261-P280-P305+P351+P338-P311 |
| Safety Statements | 24/25 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| HazardClass | 6.1(a) |
| PackingGroup | II |
| HS Code | 29419090 |
![(2R,3S)-5-(2-amino-4-methoxy-1H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol](https://img.chemicalbook.com/CAS/GIF/86392-74-7.gif)
