2-(Benzyloxy)acetyl chloride , 95%GC , 19810-31-2

CAS NO.：19810-31-2

Empirical Formula: C9H9ClO2

Molecular Weight: 184.62

MDL number: MFCD00010768

EINECS: 629-534-8

PRODUCT Properties

• Melting point: 120 °C (decomp)
• Boiling point: 84-87 °C/0.4 mmHg (lit.)
• Density: 1.17 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.523(lit.)
• Flash point: >230 °F
• storage temp.: 2-8°C
• form: Powder or Cyrstals
• color: White
• Water Solubility: Reacts with water.
• Sensitive: Moisture Sensitive
• BRN: 1947363
• InChI: InChI=1S/C9H9ClO2/c10-9(11)7-12-6-8-4-2-1-3-5-8/h1-5H,6-7H2
• InChIKey: QISAUDWTBBNJIR-UHFFFAOYSA-N
• SMILES: C(Cl)(COCC1=CC=CC=C1)=O
• CAS DataBase Reference: 19810-31-2(CAS DataBase Reference)

Description and Uses

Benzyloxyacetyl chloride is a reagent used to construct substituted 2-azetidinones for further elaboration into annulated β-lactams. It is a commonly employed reagent for asymmetric synthesis of β-lactams. It is also used in preparation of (S)-3-(methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile, key intermediate in the preparation of fluoroquinolone antibiotic for respiratory tract infections, non-racemic helicene and β-lactams.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H314
• Precautionary statements: P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
• Hazard Codes: C
• Risk Statements: 14-34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• F: 10-19
• HazardClass: 8
• PackingGroup: III
• HS Code: 29189900
• Limited Quantities: 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)