Bretylium tosylate , 98% , 61-75-6

Synonym(s):
(o-Bromobenzyl)ethyldimethylammonium p-toluenesulfonate

CAS NO.：61-75-6

Empirical Formula: C18H24BrNO3S

Molecular Weight: 414.36

MDL number: MFCD00038731

EINECS: 200-516-8

PRODUCT Properties

• Melting point: 97-99°
• storage temp.: Inert atmosphere,Room Temperature
• solubility: H2O: soluble50mg/mL
• form: Solid
• color: white
• Major Application: pharmaceutical (small molecule)
• InChI: 1S/C11H17BrN.C7H8O3S/c1-4-13(2,3)9-10-7-5-6-8-11(10)12;1-6-2-4-7(5-3-6)11(8,9)10/h5-8H,4,9H2,1-3H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1
• InChIKey: KVWNWTZZBKCOPM-UHFFFAOYSA-M
• SMILES: Cc1ccc(cc1)S([O-])(=O)=O.CC[N+](C)(C)Cc2ccccc2Br

Description and Uses

Bretylium tosylate has a biphasic response, initially inducing norepinephrine release followed by sympathetic ganglionic blockade. Bretylium tosylate is a class III antiarrhythmic agent and a competitive inhibitor of acetylcholinesterase.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302+H312+H332
• Precautionary statements: P261-P280-P301+P312+P330
• Hazard Codes: Xn
• Risk Statements: 20/21/22
• Safety Statements: 36
• WGK Germany: WGK 3
• RTECS: BO9450000
• HS Code: 2923900100
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Acute Tox. 4 Dermal; Acute Tox. 4 Inhalation; Acute Tox. 4 Oral
• Toxicity: LD50 in mice (mg/kg): 400 orally; 250 i.m. (Goldenthal)