Palbociclib-012 , 0.95 , 2206135-30-8

CAS NO.：2206135-30-8

Empirical Formula: C41H55N11O5

Molecular Weight: 781.96

MDL number:

Update time: 2023-04-23

PRODUCT Properties

Boiling point:	918.6±75.0 °C(Predicted)
Density	1.302±0.06 g/cm3(Predicted)
pka	6.28±0.10(Predicted)
InChIKey	ZXAOMPKUBCILTQ-UHFFFAOYSA-N
SMILES	O=C1C(=C(C2=CN=C(N=C2N1C1CCCC1)NC1N=CC(N2CCN(CC2)C(=O)OC(C)(C)C)=CC=1)C)NC1N=CC(N2CCN(CC2)C(=O)OC(C)(C)C)=CC=1

Description and Uses

di-tert-Butyl 4,4''-(6,6''-((8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-2,6-diyl)bis(azanediyl))bis(pyridine-6,3-diyl))bis(piperazine-1-carboxylate) is an impurity of Palbociclib (P139900) an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.

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