13(R)-HODE , ≥98% , 10219-69-9

CAS NO.：10219-69-9

Empirical Formula: C18H32O3

Molecular Weight: 296.44

MDL number: MFCD00084834

PRODUCT Properties

• Boiling point: 422.7±20.0 °C(Predicted)
• Density: 0.970±0.06 g/cm3(Predicted)
• storage temp.: Store at -20°C
• solubility: DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
• pka: 4.78±0.10(Predicted)

Description and Uses

13(R)-HODE is the opposite enantiomer of the 13(S)-HODE produced when linoleic acid is incubated with soybean lipoxygenase. The presence of 13(R)-HODE in the supernatants and membranes of cultured bovine endothelial cells has been attributed to COX metabolism.¹ 13(R)-HODE is a weak (IC₅₀ = 2.7 μM) inhibitor of U-46619-induced platelet aggregation.²

13(R)-HODE is the opposite enantiomer of the 13(S)-HODE produced when linoleic acid is incubated with soybean lipoxygenase. The presence of 13(R)-HODE in the supernatants and membranes of cultured bovine endothelial cells has been attributed to COX metabolism.1 13(R)-HODE is a weak (IC50=2.7 μM) inhibitor of U-46619-induced platelet aggregation.

Safety

• Symbol(GHS): GHS02,GHS07
• Signal word: Danger
• Hazard statements: H225-H319
• Precautionary statements: P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501