97% , 1353012-00-6

CAS NO.：1353012-00-6

Empirical Formula: C17H20F5N3O6

Molecular Weight: 457.35

MDL number: MFCD20926373

PRODUCT Properties

• storage temp.: Storage temp. 2-8°C
• solubility: Soluble in DMSO, DCM, DMF
• form: Liquid
• color: Colorless to light yellow

Description and Uses

Azido-PEG4-PFP ester is a click reagent containing an azide group and a PFP moiety. The azide group enables Click Chemistry. The PFP ester is can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules, comparing with NHS ester, PFP ester is more stable.. The hydrophilic PEG spacer adds to the water solubility of this reagent.

N3-PEG4-C2-Pfp ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG4-C2-Pfp ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Safety

• HS Code: 2942000090