L-745,870trihydrochloride , ≥98% , 158985-00-3

CAS NO.：158985-00-3

Empirical Formula: C18H19ClN4

Molecular Weight: 326.82

MDL number: MFCD01074795

PRODUCT Properties

• Boiling point: 571.4±50.0 °C(Predicted)
• Density: 1.31±0.1 g/cm3(Predicted)
• storage temp.: Desiccate at +4°C
• solubility: DMSO:16.5(Max Conc. mg/mL);50.49(Max Conc. mM)
• pka: 8.20±0.20(Predicted)
• form: Solid
• color: White to off-white
• Water Solubility: water: soluble
• InChI: 1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21)
• InChIKey: OGJGQVFWEPNYSB-UHFFFAOYSA-N
• SMILES: Clc1ccc(cc1)N2CCN(CC2)Cc3c4c([nH]c3)nccc4

Description and Uses

L-745,870 is a drug which acts as a dopamine receptor antagonist selective for the D4 subtype, and has antipsychotic effects in animal models, though it was not effective in human trials.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P280-P301+P312-P302+P352-P305+P351+P338
• WGK Germany: WGK 3
• Storage Class: 11 - Combustible Solids