LN3415749
BisindolylmaleimideII , ≥98% , 137592-45-1
| Pack Size | Price | Stock | Quantity |
| 10mg | RMB3748.00 | In Stock |
|
| 50mg | RMB15452.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 709.9±60.0 °C(Predicted) |
| Density | 1.36±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMSO: soluble |
| form | solid |
| pka | 8.17±0.60(Predicted) |
| color | Yellow to orange |
| biological source | synthetic (organic) |
| InChIKey | LBFDERUQORUFIN-UHFFFAOYSA-N |
| SMILES | CN1CCCC1CCn2cc(C3=C(C(=O)NC3=O)c4c[nH]c5ccccc45)c6ccccc26 |
Description and Uses
Bisindolylmaleimide II, is a potent ATP-competitive protein kinase C (PKC) inhibitor. In addition it inhibits PDK1 (IC50 = 14 μM), an important kinase in the insulin signaling pathway, and PKA (IC50 = 2.94 μM).
Safety
| PPE | Eyeshields, Gloves, type N95 (US) |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
