98% , 74050-20-7

CAS NO.：74050-20-7

Empirical Formula: C26H36O7

Molecular Weight: 460.56

MDL number: MFCD00866010

PRODUCT Properties

• Melting point: 144-146°C
• Density: 1.23±0.1 g/cm3 (20 ºC 760 Torr)
• storage temp.: Refrigerator
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: Solid
• color: White to Pale Beige
• InChIKey: MFBMYAOAMQLLPK-VRVFYZPPNA-N
• SMILES: [C@@]1(OC(=O)CC)(C(=O)COC(=O)C)CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]12C |&1:0,15,17,27,29,31,34,r|

Description and Uses

Hydrocortisone aceponate is the 17-a-propionate derivative of hydrocortisone-21-acetate. Its is reportedly significantly superior to the latter in the treatment of dermatoses of varying severity.

A new topical hydrocortisone derivative with esterification in positions 17 and 21, inhibit the incorporation of [3H]thymidine in DNA in human skin fibroblasts less strongly than the halogenated glucocorticosteroids betamethasone 17-valerate and clobetasol 17-propionate. Glucocorticosteroid.

Safety

• Symbol(GHS): GHS08
• Signal word: Danger
• Hazard statements: H360