Home Categories N-(4-chloro-3-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
LN7885957

N-(4-chloro-3-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine , 1603814-04-5

CAS NO.:1603814-04-5

Empirical Formula: C22H24ClFN4O3

Molecular Weight: 446.9

MDL number:

Pack Size Price Stock Quantity
1g RMB3520.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 180-183oC
Boiling point: 585.0±50.0 °C(Predicted)
Density  1.322±0.06 g/cm3(Predicted)
storage temp.  Refrigerator
solubility  Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form  Solid
pka 7.00±0.10(Predicted)
color  Off-White to Light Brown
Major Application pharmaceutical

Description and Uses

3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib is an impurity of Gefitinib (G304000); a tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR).

Safety

Symbol(GHS) 
GHS08,GHS05,GHS07,GHS09
Signal word  Danger
Hazard statements  H302-H315-H318-H351-H360Fd-H373-H411
Precautionary statements  P273-P280-P301+P312-P302+P352-P305+P351+P338-P308+P313
WGK Germany  WGK 3
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 4 Oral
Aquatic Chronic 2
Carc. 2
Eye Dam. 1
Repr. 1B
Skin Irrit. 2
STOT RE 2 Oral

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