PRODUCT Properties
| Melting point: | 144 - 150°C |
| Density | 1.61±0.1 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | DMF (Slightly, Heated), DMSO (Slightly) |
| pka | 3.49±0.10(Predicted) |
| color | Pale Brown to Brown |
| Major Application | pharmaceutical (small molecule) |
| InChIKey | HLIXOCXUWGDBNP-UHFFFAOYSA-N |
| SMILES | N(Cc2nc3c(nc(nc3O)N)nc2)(C)c1ccc(cc1)C(=O)NC(CCC(=O)O)C(=O)O |
Description and Uses
2-[(2-Hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxylic Acid is an impurity of Acotiamide (A190260), an acetylcholinesterase inhibitor which has been shown to stimulate gastric motility and improve gastric motility dysfunction in rats. Acotiamide Hydrochloride has also been shown to improve meal-related symptoms of functional dyspepsia.
Safety
| Symbol(GHS) |   GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H301-H315-H319-H341-H360 |
| Precautionary statements | P201-P301+P310+P330-P302+P352-P305+P351+P338 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| HS Code | 2933599550 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral Eye Irrit. 2 Muta. 2 Repr. 1B Skin Irrit. 2 |
