M4507335
Niranthin , 96% , 50656-77-4
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB2083.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 559.5±50.0 °C(Predicted) |
| Density | 1.142±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 15 mg/ml,DMSO: 10 mg/ml,Ethanol: 5 mg/ml |
| InChI | 1S/C24H32O7/c1-25-13-18(8-16-6-7-20(27-3)21(10-16)28-4)19(14-26-2)9-17-11-22(29-5)24-23(12-17)30-15-31-24/h6-7,10-12,18-19H,8-9,13-15H2,1-5H3/t18-,19-/m0/s1 |
| InChIKey | RCFGIEPQSDGMJJ-OALUTQOASA-N |
| SMILES | COC1=C(OCO2)C2=CC(C[C@H](COC)[C@@H](COC)CC3=CC=C(OC)C(OC)=C3)=C1 |
Description and Uses
rac-Niranthin is a lignan compound isolated from the plant Phyllanthus amarus and shows anti-leishmanial activity. It acts through induction of topoisomerase I-mediated DNA-protein adduct formation in Leishmania cells triggering apoptosis of cellular nucleases. It also maintains the ability to reduce uric acid concentrations through xanthine oxidase inhibition.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
