M5576835
SRT2104(GSK2245840) , 99% , 1093403-33-8
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB900.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.46±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | insoluble in H2O; insoluble in EtOH; ≥6.46 mg/mL in DMSO with gentle warming |
| form | Powder |
| pka | 11.40±0.70(Predicted) |
| color | Light yellow to yellow |
| InChIKey | LAMQVIQMVKWXOC-UHFFFAOYSA-N |
| SMILES | S1C(C(NC2=CC=CC=C2C2=CN3C(CN4CCOCC4)=CSC3=N2)=O)=C(C)N=C1C1=CC=CN=C1 |
Description and Uses
SRT 2104 is a first-in-class, highly selective and brain-permeable activator of the NAD+ dependent deacetylase Sirt1, increases Sirt1 protein, but shows no effect on Sirt1 mRNA. Used in the research of diabetes mellitus and Huntington’s disease[1][2][3].
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
