SofosbuvirimpurityF? , ≥97% , 1337482-17-3

CAS NO.：1337482-17-3

Empirical Formula: C34H45FN4O13P2

Molecular Weight: 798.69

MDL number:

PRODUCT Properties

• Density: 1.37±0.1 g/cm3(Predicted)
• storage temp.: Store at -20°C
• solubility: Soluble in DMSO
• form: Solid
• pka: 9.39±0.10(Predicted)
• color: Light yellow to yellow

Description and Uses

Sofosbuvir 3'',5''-Bis-(S)-phosphate is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.