M5817235
TubastatinA , 99% , 1252003-15-8
| Pack Size | Price | Stock | Quantity |
| 25mg | RMB630.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.28±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | insoluble in EtOH; insoluble in H2O; ≥10.75 mg/mL in DMSO |
| form | solid |
| pka | 8.95±0.10(Predicted) |
| color | Off-white to light yellow |
| InChI | InChI=1S/C20H21N3O2/c1-22-11-10-19-17(13-22)16-4-2-3-5-18(16)23(19)12-14-6-8-15(9-7-14)20(24)21-25/h2-9,25H,10-13H2,1H3,(H,21,24) |
| InChIKey | GOVYBPLHWIEHEJ-UHFFFAOYSA-N |
| SMILES | C(NO)(=O)C1=CC=C(CN2C3=C(C=CC=C3)C3CN(C)CCC2=3)C=C1 |
Description and Uses
Tubastatin A is a potent and selective HDAC6 inhibitor with an IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A also inhibits HDAC10 and metallo-β-lactamase domain-containing protein 2 (MBLAC2).
