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M6090335

Toremifene , 98% , 89778-26-7

CAS NO.:89778-26-7

Empirical Formula: C26H28ClNO

Molecular Weight: 405.96

MDL number: MFCD00801070

Pack Size Price Stock Quantity
100mg RMB820.80 In Stock
500mg RMB2384.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 108-110°C
Boiling point: 535.1±50.0 °C(Predicted)
Density  1.104±0.06 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  25℃: DMSO 120mg/mL ;Water <1mg/mL; Ethanol <1mg/mL
pka 8.69±0.28(Predicted)
form  Powder
color  White to light yellow
Stability: Light sensitive
InChI InChI=1S/C26H28ClNO/c1-28(2)19-20-29-24-15-13-23(14-16-24)26(22-11-7-4-8-12-22)25(17-18-27)21-9-5-3-6-10-21/h3-16H,17-20H2,1-2H3/b26-25-
InChIKey XFCLJVABOIYOMF-QPLCGJKRSA-N
SMILES C(/C1C=CC=CC=1)(\C1C=CC(=CC=1)OCCN(C)C)=C(\C1C=CC=CC=1)/CCCl
CAS DataBase Reference 89778-26-7(CAS DataBase Reference)
IARC 3 (Vol. 66) 1996

Description and Uses

Toremifene is an antiestrogenic anticancer agent effective in the treatment of advanced recurrent breast cancer in postmenopausal patients. It is claimed to be more effective than tamoxifen in several rat mammary tumor models. Side-effects are mild, including hot flushes and sweating.

An antiestrogen and antineoplastic. Nonsteroidal antiestrogen structurally similar to tamoxifen

Safety

Symbol(GHS) 
GHS05,GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H318-H400-H410
Precautionary statements  P264-P280i-P301+P312a-P305+P351+P338-P310a-P501a
HazardClass  9

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