M7455348
3,3-Bis(aminoethyl)-1-hydroxy-2-oxo-1-triazene , 97% , 146724-94-9
Synonym(s):
DETA NONOate;NOC-18;DETA/NO, 2,2?-(Hydroxynitrosohydrazino) bis-ethanamine, DETA NONOate;DETA/NO, 2,2?-(Hydroxynitrosohydrazino)bis-ethanamine, DETA NONOate;2,2′-(Hydroxynitrosohydrazino)bis-ethanamine
| Pack Size | Price | Stock | Quantity |
| 25mg | RMB1200.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 98-106 °C |
| Boiling point: | 290.26°C (rough estimate) |
| Density | 1.3102 (rough estimate) |
| refractive index | 1.8000 (estimate) |
| storage temp. | -20°C |
| solubility | H2O: >20 mg/mL |
| pka | 4.50±0.69(Predicted) |
| form | solid |
| color | off-white |
| Water Solubility | PBS, pH 7.4: 100mg/mL 10 mM NaOH: soluble water: soluble |
| Stability: | Stable for 1 year from date of purchase as supplied. Store under inert gas. Solutions must be made fresh immediately before use and cannot be stored. |
| InChI | 1S/C4H12N5O2/c5-1-3-8(4-2-6)9(11)7-10/h1-6H2/q-1/p+1 |
| InChIKey | PAOXTYJXTPPVHU-UHFFFAOYSA-O |
| SMILES | NCCN(CC[NH3+])N([O-])N=O |
| CAS DataBase Reference | 146724-94-9 |
Description and Uses
DETA NONOate (146724-94-9) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner. The half-life of DETA NONOate in 0.1 M phosphate buffer at pH 7.4 is 20 hours at 37°C, or 56 hours at room temperature.1?Dissociation is essentially instantaneous at a pH of 5.0.
3,3-Bis(aminoethyl)-1-hydroxy-2-oxo-1-triazene has been used as a nitric oxide donor supplement for neuronal culture. It has also been used as a nitric oxide donor to study the effects of protein S-nitrosation (SNO) after nitrite treatment.
Safety
| Symbol(GHS) |  GHS02 |
| Signal word | Danger |
| Hazard statements | H242 |
| Precautionary statements | P210-P234-P235-P240-P370+P378-P403 |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| RTECS | KH2502500 |
| HS Code | 29270000 |
| Storage Class | 5.2 - Organic peroxides and self-reacting hazardous materials |
| Hazard Classifications | Self-react. C |
