Selumetinibsulfate(AZD6244sulfate) , 98% , 943332-08-9

CAS NO.：943332-08-9

Empirical Formula: C17H17BrClFN4O7S

Molecular Weight: 555.76

MDL number:

PRODUCT Properties

• storage temp.: Store at -20°C
• solubility: DMSO: 50 mg/mL (89.97 mM); Water: < 0.1 mg/mL (insoluble)
• form: Solid
• color: Light yellow to yellow
• InChIKey: GRKFGZYYYYISDX-UHFFFAOYSA-N
• SMILES: S(O)(O)(=O)=O.N(C1C=CC(Br)=CC=1Cl)C1C(=C2N=CN(C)C2=CC=1C(=O)NOCCO)F
• CAS DataBase Reference: 943332-08-9

Description and Uses

Selumetinib Sulfate (Koselugo) is a selective ATP-noncompetitive MEK1/2 inhibitor developed by Array BioPharma for the treatment of neurofibromatosis type 1 (NF1).

Safety

• Symbol(GHS): GHS07,GHS08,GHS09,GHS05
• Signal word: Danger
• Hazard statements: H411-H317-H361-H318-H373
• Precautionary statements: P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P201-P202-P281-P308+P313-P405-P501-P280-P305+P351+P338-P310-P260-P314-P501