M6242235
Volitinib , 99% , 1313725-88-0
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB522.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 205-207°C |
| Density | 1.55±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 5.67±0.50(Predicted) |
| form | Solid |
| color | Pale Beige |
| InChI | InChI=1S/C17H15N9/c1-11(12-3-4-15-18-5-6-25(15)10-12)26-17-16(22-23-26)19-8-14(21-17)13-7-20-24(2)9-13/h3-11H,1-2H3/t11-/m0/s1 |
| InChIKey | XYDNMOZJKOGZLS-NSHDSACASA-N |
| SMILES | C12N=NN([C@H](C3=CN4C=CN=C4C=C3)C)C1=NC(C1=CN(C)N=C1)=CN=2 |
| CAS DataBase Reference | 1313725-88-0 |
Description and Uses
Savolitinib selectively inhibits the MET receptor, blocking the PI3K/AKT/MAPK-signaling pathway as well as downregulating MYC.
Savolitinib is a potent and highly selective c-Met inhibitor. Savoltinib demonstrated anti-tumor efficacy in a panel of cMet-dysregulated gastric cancer PDX models. Savolitinib also demonstrated good antitmuor activities.
