NaturallyoccurringalkaloidthatblocksthereleaseofCa2+fromthesarcoplasmicreticulum. , 15662-33-6

Synonym(s):
Ryanodine, High Purity - CAS 15662-33-6 - Calbiochem

CAS NO.：15662-33-6

Empirical Formula: C25H35NO9

Molecular Weight: 493.55

MDL number: MFCD00151119

EINECS: 239-732-2

PRODUCT Properties

• alpha: D25 +26° (methanol)
• Boiling point: 586.95°C (rough estimate)
• Density: 1.2805 (rough estimate)
• refractive index: 1.6000 (estimate)
• storage temp.: Sealed in dry,2-8°C
• solubility: DMSO: soluble10mg/mL, clear
• form: White solid
• Melting point: 219-220 °C
• pka: 10.66±0.70(Predicted)
• color: white to beige
• Water Solubility: water: 1mg/mL; methanol: 20mg/mL
• InChIKey: JJSYXNQGLHBRRK-YSOSZROBSA-N
• SMILES: [nH]1c(ccc1)C(=O)O[C@H]2[C@@]3([C@]4([C@]65O[C@]([C@]4([C@@]2(O)C(C)C)C)(C[C@]3([C@]6(CC[C@@H]([C@H]5O)C)O)C)O)O)O
• CAS DataBase Reference: 15662-33-6
• EPA Substance Registry System: Ryanodine (15662-33-6)

Description and Uses

Ryania insecticide is the ground stem wood of the tropical tree Ryania speciosa Vahl., and it contains over a dozen of several structurally related alkaloids. Nowadays, this botanical preparation is of minor importance, but one of its major ingredients, ryanodine, is a widely used pharmacological tool in studies of the calcium release channels in sarcoplasmic reticulum membranes of skeletal and cardiac muscle of both insects and mammals (11,12).

Insecticide.

Safety

• Symbol(GHS): GHS07,GHS09
• Signal word: Warning
• Hazard statements: H302+H312-H410
• Precautionary statements: P264-P270-P273-P280-P301+P312-P302+P352+P312
• Hazard Codes: Xn,N
• Risk Statements: 21/22-50/53
• Safety Statements: 36/37-60-61
• RIDADR: UN 3077 9/PG 3
• WGK Germany: WGK 3
• RTECS: VM4025000
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Acute Tox. 4 Dermal; Acute Tox. 4 Oral; Aquatic Acute 1; Aquatic Chronic 1