S2796749
ManassantinA , phyproof ReferenceSubstance , 88497-87-4
Synonym(s):
Saucernetin A
| Pack Size | Price | Stock | Quantity |
| 10mg | RMB7791.38 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 82-85℃ |
| Boiling point: | 836.0±65.0 °C(Predicted) |
| Density | 1.172±0.06 g/cm3 (20 ºC 760 Torr) |
| storage temp. | 2-8°C |
| pka | 13.05±0.20(Predicted) |
| form | solid |
| InChIKey | UOJVSXNASPZQFU-UHFFFAOYSA-N |
| SMILES | O1C(C(C(C1c4cc(c(cc4)OCCC(O)c5cc(c(cc5)OC)OC)OC)C)C)c2cc(c(cc2)OCCC(O)c3cc(c(cc3)OC)OC)OC |
Description and Uses
Manassantin A is a potent inhibitor of hypoxia-inducible factor 1 (HIF-1) activity. Also, it is an herbal medicine isolated from Saururus chinensis which inhibits 5-lipoxygenase (5-LO)-dependent leukotriene C4 (LTC4) generation in bone marrow-derived mast cells (BMMCs)
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302+H332-H319-H335 |
| Precautionary statements | P301+P312+P330-P304+P340+P312-P305+P351+P338 |
| target organs | Respiratory system |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Inhalation Acute Tox. 4 Oral Eye Irrit. 2 STOT SE 3 |
