[3-(Ethoxycarbonyl)-2-oxopropyl]triphenylphosphonium chloride , 106302-03-8

CAS NO.：106302-03-8

Empirical Formula: C24H24ClO3P

Molecular Weight: 426.87

MDL number: MFCD00192128

PRODUCT Properties

• Melting point: 160 °C (dec.)(lit.)
• InChI: 1S/C24H24O3P.ClH/c1-2-27-24(26)18-20(25)19-28(21-12-6-3-7-13-21,22-14-8-4-9-15-22)23-16-10-5-11-17-23;/h3-17H,2,18-19H2,1H3;1H/q+1;/p-1
• InChIKey: BRRCLIKFZISBBV-UHFFFAOYSA-M
• SMILES: [Cl-].CCOC(=O)CC(=O)C[P+](c1ccccc1)(c2ccccc2)c3ccccc3

Description and Uses

Reactant for:

• Preparation of cyclic amidine-based inhibitors of ?-secretase (BACE-1)
• Wittig reactions
• Dehydrochlorination and alkylation reactions

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• target organs: Respiratory system
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2; Skin Irrit. 2; STOT SE 3