suitableforfluorescence,≥95%(HPCE) , 18323-58-5

Synonym(s):
Oleic acid 4-methylumbelliferyl ester

CAS NO.：18323-58-5

Empirical Formula: C28H40O4

Molecular Weight: 440.61

MDL number: MFCD00076095

EINECS: 242-210-7

PRODUCT Properties

• Melting point: 37-38 °C (lit.)
• Boiling point: 471.81°C (rough estimate)
• Density: 1.023
• refractive index: 1.4840 (estimate)
• Flash point: 281.3℃
• storage temp.: -20°C
• solubility: 2-methoxyethanol: soluble
• form: Solid
• color: Colorless to Pale Yellow Oil
• Appearance: Solid Powder
• BRN: 4887028
• InChI: 1S/C28H40O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-27(29)31-24-19-20-25-23(2)21-28(30)32-26(25)22-24/h10-11,19-22H,3-9,12-18H2,1-2H3/b11-10-
• InChIKey: NKQFKJYKCVDLPT-KHPPLWFESA-N
• SMILES: CCCCCCCC\C=C/CCCCCCCC(=O)Oc1ccc2C(C)=CC(=O)Oc2c1
• CAS DataBase Reference: 18323-58-5(CAS DataBase Reference)

Description and Uses

4-Methylumbelliferyl (4-MU) oleate is a fluorogenic substrate for acid and alkaline lipases. It is cleaved by lipases, liberating 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.

4-Methylumbelliferyl oleate has been used:

• as a substrate to assay the activity of non-specific esterases
• to determine lipase activity
• as a substrate to evaluate pancreatic lipase inhibitory activity

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P280-P301+P312-P302+P352-P305+P351+P338
• PPE: Eyeshields, Gloves, type N95 (US)
• WGK Germany: 3
• F: 8-10
• HS Code: 29322090
• Storage Class: 11 - Combustible Solids