Acetyl coenzyme?A sodium salt , ≥93%(HPLC),powder , 102029-73-2

Synonym(s):
acetyl-coa

CAS NO.：102029-73-2

Empirical Formula: C23H38N7O17P3S.3Na

Molecular Weight: 809.57

MDL number: MFCD00078858

PRODUCT Properties

• storage temp.: -20°C
• solubility: H₂O: 100 mg/mL
• form: powder
• color: White to off-white
• Water Solubility: H2O: 100mg/mL
• InChIKey: ZSLZBFCDCINBPY-KMYLAXNMSA-N
• SMILES: [NaH].[NaH].[NaH].O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)C)O[C@H]1N1C=NC2C(=NC=NC1=2)N)OP(O)(O)=O |&1:4,5,6,21,38,r|

Description and Uses

Acetyl-coenzyme A (acetyl-CoA), the thioester of CoA and acetic acid, is a pivotal molecule in biological systems. Foremost, it serves as a source of carbon for the Krebs cycle, for the synthesis of fatty acids, and for isoprenoid-based protein modifications. Acetyl-CoA also serves as an intermediate in oxidation of fatty acids and amino acids and is formed by the oxidative decarboxylation of pyruvate in mitochondria. It is an essential cofactor or substrate for acetyltransferases and acyltransferases, as in the post-translational modification of proteins and in the synthesis of the neurotransmitter acetylcholine.

Acetyl-Coenzyme A is used to assay CAT enzyme activity in cell extracts using radioisotopes. CAT enzyme activity in cell extracts catalyzes the transfer of acetyl groups from acetylcoenzyme A to chloramphenicol. A number of assays have been developed to measure CAT activity in cell extracts. Acetyl-Coenzyme A has also been used to determine citrate synthase activity.

Safety

• Symbol(GHS): GHS08
• Signal word: Danger
• Hazard statements: H370
• Precautionary statements: P260-P264-P270-P307+P311-P321-P405-P501
• Risk Statements: 23/24/25-36/38-39/23/24/25-66-67
• Safety Statements: 24-36/37-45
• WGK Germany: 1
• F: 3-10-21
• HS Code: 29349990