S8923014
≥98%(HPLC),powder , 51116-01-9
Synonym(s):
8-Br-cGMP;8-Bromo-cGMP, Br-cGMP, Na;8-Bromo-cyclic GMP;Guanosine 3ʹ,5ʹ-cyclic Monophosphate, 8-Bromo-, Sodium Salt - CAS 51116-01-9 - Calbiochem
CAS NO.：51116-01-9
Empirical Formula: C10H10BrN5O7P.Na
Molecular Weight: 446.08
MDL number: MFCD03703483
EINECS: 256-993-8
| Pack Size | Price | Stock | Quantity |
| 10mg | RMB779.51 | In Stock |
|
| 25mg | RMB1568.34 | In Stock |
|
| 100mg | RMB5961.74 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| storage temp. | -20°C |
| solubility | H2O: 100 mg/mL |
| form | powder |
| color | White to off-white |
| Water Solubility | Soluble to 100 mM in water |
| InChIKey | ZJRFCXHKYQVNFK-YEOHUATISA-M |
| SMILES | [Na+].NC1=Nc2c(nc(Br)n2[C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)C(=O)N1 |
Description and Uses
8-bromo-Cyclic GMP (8-bromo-cGMP) is a cell-permeable analog of cGMP that exhibits greater resistance to hydrolysis by phosphodiesterases than its parent compound. It preferentially activates cGMP-dependent protein kinase. At 1 μM-0.1 mM, 8-bromo-cGMP can inhibit acetylcholine-induced increases in intracellular calcium concentrations.
8-bromo-cGMP activates cGMP-dependent protein kinase. It can also inhibit acetylcholine-induced increases in intracellular calcium concentrations.
Safety
| PPE | Eyeshields, Gloves, type N95 (US) |
| WGK Germany | 3 |
| F | 10-21 |
| HS Code | 29349990 |
| Storage Class | 11 - Combustible Solids |
