S9063114
≥98%(HPLC),powder , 418805-02-4
Synonym(s):
4[4-(5-Nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl]-benzoic acid ethyl ester
Pack Size | Price | Stock | Quantity |
5mg | RMB830.68 | In Stock |
|
25mg | RMB2526.46 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 228 - 235°C |
Density | 1.486±0.06 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | Soluble in DMSO at 5mg/ml with warming |
form | powder |
pka | 7.43±0.20(Predicted) |
color | red to brown |
Sensitive | Light Sensitive |
Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week. |
InChI | InChI=1S/C17H13N3O7/c1-2-26-17(23)10-3-5-11(6-4-10)19-16(22)13(15(21)18-19)9-12-7-8-14(27-12)20(24)25/h3-9H,2H2,1H3,(H,18,21) |
InChIKey | ARGIPZKQJGFSGQ-LCYFTJDESA-N |
SMILES | C(OCC)(=O)C1=CC=C(N2C(=O)C(=CC3=CC=C([N+]([O-])=O)O3)C(=O)N2)C=C1 |
Description and Uses
Pyr41 (418805-02-4) inhibits ubiquitin activating enzyme E1 (>60% inhibition at 10 μM) with little or no activity against E2 or E3. Cell permeable
PYR 41 is an irreversible and cell-permeable UBE1 inhibitor.