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S9063114

≥98%(HPLC),powder , 418805-02-4

Synonym(s):
4[4-(5-Nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl]-benzoic acid ethyl ester

CAS NO.:418805-02-4

Empirical Formula: C17H13N3O7

Molecular Weight: 371.3

MDL number:

Pack Size Price Stock Quantity
5mg RMB830.68 In Stock
25mg RMB2526.46 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 228 - 235°C
Density  1.486±0.06 g/cm3(Predicted)
storage temp.  -20°C
solubility  Soluble in DMSO at 5mg/ml with warming
form  powder
pka 7.43±0.20(Predicted)
color  red to brown
Sensitive  Light Sensitive
Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
InChI InChI=1S/C17H13N3O7/c1-2-26-17(23)10-3-5-11(6-4-10)19-16(22)13(15(21)18-19)9-12-7-8-14(27-12)20(24)25/h3-9H,2H2,1H3,(H,18,21)
InChIKey ARGIPZKQJGFSGQ-LCYFTJDESA-N
SMILES C(OCC)(=O)C1=CC=C(N2C(=O)C(=CC3=CC=C([N+]([O-])=O)O3)C(=O)N2)C=C1

Description and Uses

Pyr41 (418805-02-4) inhibits ubiquitin activating enzyme E1 (>60% inhibition at 10 μM) with little or no activity against E2 or E3. Cell permeable

PYR 41 is an irreversible and cell-permeable UBE1 inhibitor.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280-P301+P312+P330-P302+P352
Hazard Codes  Xn
Risk Statements  22-43
Safety Statements  36/37
WGK Germany  3

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