phospodiesteraseandADP-ribosylcyclasesubstrate , 5624-35-1

Synonym(s):
;NGD

CAS NO.：5624-35-1

Empirical Formula: C21H27N7O15P2

Molecular Weight: 679.42

MDL number: MFCD00079505

PRODUCT Properties

• storage temp.: -20°C
• solubility: H₂O: soluble-50 mg/mL, clear, almost colorless to slightly yellow
• form: powder
• InChIKey: WWXCUPZEUROLRY-UHFFFAOYSA-N
• SMILES: NC(=O)C1=CC=C[N](=C1)C2OC(COP(O)(=O)OP(O)(=O)OCC3OC(C(O)C3O)n4cnc5C(=O)N=C(N)Nc45)C(O)C2O

Description and Uses

Nicotinamide guanine dinucleotide sodium salt has been used as a substrate for measuring the cyclase activity of the enzyme cluster of differentiation 38 (CD38). It has also been used as a substrate to fluorometrically determine the activity of CD38/ADP-ribose (ADPR).

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• target organs: Respiratory system
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 22-26-36
• WGK Germany: 3
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2; Skin Irrit. 2; STOT SE 3