Ala-Gln , 98% , 39537-23-0

Synonym(s):
Ala-Gln;Alanyl-glutamine;Glutamine-S

CAS NO.：39537-23-0

Empirical Formula: C8H15N3O4

Molecular Weight: 217.22

MDL number: MFCD00133046

EINECS: 475-290-9

PRODUCT Properties

• Melting point: 215 °C
• Boiling point: 615℃
• Density: 1.305±0.06 g/cm3(Predicted)
• vapor pressure: 0-1000Pa at 20-313.7℃
• FEMA: 4712 | L-ALANYL-L-GLUTAMINE
• RTECS: MA2275262
• refractive index: 10 ° (C=5, H2O)
• Flash point: >110°(230°F)
• storage temp.: 2-8°C
• solubility: Water (Sparingly)
• form: solution
• pka: 3.12±0.10(Predicted)
• color: White
• PH: pH(50g/l, 25℃) : 5.0～6.0
• Odor: mild savory
• optical activity: Consistent with structure
• Water Solubility: Soluble in water.
• JECFA Number: 2121
• Stability: Hygroscopic
• Cosmetics Ingredients Functions: HUMECTANT; SKIN CONDITIONING
• InChI: 1S/C8H15N3O4/c1-4(9)7(13)11-5(8(14)15)2-3-6(10)12/h4-5H,2-3,9H2,1H3,(H2,10,12)(H,11,13)(H,14,15)/t4-,5-/m0/s1
• InChIKey: HJCMDXDYPOUFDY-AKGZTFGVSA-N
• SMILES: NC(CC[C@H](NC([C@@H](N)C)=O)C(O)=O)=O
• LogP: -4.6 at 22℃ and pH6.3
• Surface tension: 70mN/m at 1g/L and 20℃
• CAS DataBase Reference: 39537-23-0(CAS DataBase Reference)

Description and Uses

L-Alanyl-L-glutamine is a synthetic glutamine dipeptide that can attenuate oxidative stress in rodent models when administered at doses of 0.75-1.5 mg/kg. In vivo, the parenteral administration of L-alanyl-L-glutamine to Swiss mice yields higher plasma glutamine levels compared to enteral administration. In vitro, the addition of this dipeptide (50 mM) to cultures of antibody-producing CHO cells reduces apoptosis and promotes antibody production. Treatment of insulin-secreting BRIN-BD11 β-cells with L-alanyl-L-glutamine (2 mM) protects against the inflammatory effects of exposure to lipopolysaccharide-treated primary macrophages.

This supplement provides a stable form of L-glutamine while in solution.

Safety

• PPE: Eyeshields, Gloves, type N95 (US)
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 23-24/25-36-26
• WGK Germany: 1
• HS Code: 29241990
• Storage Class: 11 - Combustible Solids