Azido-PEG4-Azide

Synonym(s):
Azido-PEG3-azido;Bis-PEG3-Azide

CAS NO.：

Empirical Formula: C8H16N6O3

Molecular Weight: 244.25

MDL number: MFCD03425545

PRODUCT Properties

• Density: 1.170 g/mL at 25 °C
• refractive index: n20/D1.470
• storage temp.: -20°C
• solubility: Soluble in chloroform, DCM, DMF, DMSO, or THF
• form: Oil
• color: Clear Colourless
• Appearance: colorless liquid
• Boiling point: 163-196°C/760 mmHg
• InChI: InChI=1S/C8H16N6O3/c9-13-11-1-3-15-5-7-17-8-6-16-4-2-12-14-10/h1-8H2
• InChIKey: SFMMXKLNFMIUCH-UHFFFAOYSA-N
• SMILES: O(CCOCCN=[N+]=[N-])CCOCCN=[N+]=[N-]

Description and Uses

PEG4 diazide is a hydrophilic linker with two azide groups. Both can be modified by click chemistry, either by a copper catalyzed reaction with terminal alkynes, or by a copper-free reaction with cycloalkynes. Azides can also participate in the Staudinger ligation reaction.

This diazide is useful for the synthesis of dimeric molecules by click chemistry.

Homobifunctional PEG azide click chemistry linker. Azide functional groups will react via a copper catalyzed or strain promoted 1,3-dipolar cycloaddition click reaction with terminal alkynes and cyclooctyne derivatives to yield a stable triazole linkage.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335-H302
• Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a
• Hazard Codes: Xn
• Risk Statements: 22
• Safety Statements: 24/25
• WGK Germany: 3
• HS Code: 29270000