A0771112
AG14361 , ≥98% , 328543-09-5
| Pack Size | Price | Stock | Quantity |
| 5MG | RMB774.40 | In Stock |
|
| 10MG | RMB1279.20 | In Stock |
|
| 50MG | RMB4479.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.27 |
| storage temp. | Store at -20°C |
| solubility | insoluble in H2O; ≥10.14 mg/mL in EtOH with gentle warming and ultrasonic; ≥16 mg/mL in DMSO |
| form | solid |
| pka | 14.05±0.20(Predicted) |
| color | White to off-white |
| InChI | InChI=1S/C19H20N4O/c1-22(2)12-13-6-8-14(9-7-13)18-21-16-5-3-4-15-17(16)23(18)11-10-20-19(15)24/h3-9H,10-12H2,1-2H3,(H,20,24) |
| InChIKey | SEKJSSBJKFLZIT-UHFFFAOYSA-N |
| SMILES | N12C(C3=CC=C(CN(C)C)C=C3)=NC3=C1C(=CC=C3)C(=O)NCC2 |
Description and Uses
AG14361 is a potent PARP-1 inhibitor, with a Ki of < 5 nM, and in permeabilized SW620 and intact SW620 cells, the IC50s are 29 nM and 14 nM, respectively.
