2-Amino-6-bromobenzonitrile , 95% , 77326-62-6
| Pack Size | Price | Stock | Quantity |
| 250MG | RMB25.04 | In Stock |
|
| 1G | RMB62.40 | In Stock |
|
| 5G | RMB221.60 | In Stock |
|
| 25g | RMB690.40 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 152-154℃ |
| Boiling point: | 343.3±32.0 °C(Predicted) |
| Density | 1.68 |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 0.74±0.10(Predicted) |
| form | Powder |
| color | Off-white |
| CAS DataBase Reference | 77326-62-6 |
Description and Uses
2-amino-6-bromobenzonitrile is a versatile building block that can be used to create a range of compounds, such as 4'-methoxy-3-(phenylethynyl)-[1,1'-biphenyl]-2-carbonitrile, etc.
Substituted phenylboronic acid (6 mmol), 2-amino-6-bromobenzonitrile (5 mmol), PdCl2(PPh3)2 (35.0 mg, 0.05 mmol) and Cs2CO3 (4.89 g, 15.0 mmol) were added in CH3CN (20 mL) and H2O (1.6 mL). The reaction mixture was stirred at 80 she℃ under an argon atmosphere for 12 h. After the reaction, the mixture was cooled to room temperature and extracted with EtOAc (40 × 3 mL). The combined organic phase was washed with brine (40 mL), and dried over anhydrous MgSO4. The solvent was removed under vacuum to give the crude product C without further purification.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H312-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P304+P340-P305+P351+P338-P405-P501a |
| RIDADR | UN2811 |
| HazardClass | IRRITANT |
| HazardClass | 6.1 |
| HS Code | 2926907090 |
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
