N-tert-Butyl-α-phenylnitrone , 95% , 3376-24-7

Synonym(s):
N-Benzylidene-tert-butylamine N-oxide;N-tert-Butyl-α-phenylnitrone;PBN;Phenyl N-t-butylnitrone;Phenyl-N-tert-butylnitrone

CAS NO.：3376-24-7

Empirical Formula: C11H15NO

Molecular Weight: 177.24

MDL number: MFCD00008799

EINECS: 222-168-6

PRODUCT Properties

• Melting point: 73-74 °C(lit.)
• Boiling point: 283℃
• Density: 0.990
• refractive index: 1.5480 (estimate)
• Flash point: 119℃
• storage temp.: Store at <= 20°C.
• solubility: DMSO: soluble
• form: powder
• pka: 1.50±0.53(Predicted)
• color: white
• Water Solubility: Soluble in DMSO (10 mg/ml), chloroform (50 mg/ml), and water (20 mg/ml).
• Merck: 14,7056
• BRN: 2044028
• CAS DataBase Reference: 3376-24-7(CAS DataBase Reference)
• EPA Substance Registry System: 2-Propanamine, 2-methyl-N-(phenylmethylene)-, N-oxide (3376-24-7)

Description and Uses

N-tert-Butyl-α-phenylnitrone has been used:

• as a component of Dneasy Blood&Tissue buffer to preserve the oxidized state of DNA extracted from human non-tumorigenic epithelial breast (MCF10A) cells
• as a free radical scavenger of reactive oxygen species (ROS) in microglial (MG) cell lines
• to attenuate fibroblast senescence in unstable oral squamous cell carcinomas (GU-OSCC)

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P280-P305+P351+P338
• Safety Statements: 22-24/25
• WGK Germany: 3
• RTECS: TX1760000
• F: 10
• TSCA: Yes
• HS Code: 2929 90 00