N,N′-Dicyclohexylcarbodiimide , 99% , 538-75-0

Synonym(s):
DCC;N,N′-Dicyclohexylcarbodiimide;DCC impregnated tablets;ChemDose, N,N′-Dicyclohexylcarbodiimide impregnated tablets;N,N′-Methanetetraylbis[cyclohexanamine]

CAS NO.：538-75-0

Empirical Formula: C13H22N2

Molecular Weight: 206.33

MDL number: MFCD00011659

EINECS: 208-704-1

PRODUCT Properties

• Melting point: 34-35 °C(lit.)
• Boiling point: 122-124 °C6 mm Hg(lit.)
• bulk density: 920kg/m3
• Density: 1.247 g/mL at 25 °C
• vapor pressure: 1.044-1.15Pa at 20-25℃
• refractive index: n20/D 1.48
• Flash point: 190 °F
• storage temp.: Store below +30°C.
• solubility: methylene chloride: 0.1 g/mL, clear, colorless
• form: Waxy Solid or Crystalline Mass
• Specific Gravity: 1.247
• color: White to pale yellow
• Sensitive: Moisture Sensitive
• Merck: 14,3096
• BRN: 610662
• Stability: Stable, but moisture sensitive. Combustible. Incompatible with strong oxidizing agents. Avoid exposure to air or moisture.
• InChIKey: QOSSAOTZNIDXMA-UHFFFAOYSA-N
• LogP: 5.567-6.83 at 25℃
• CAS DataBase Reference: 538-75-0(CAS DataBase Reference)
• NIST Chemistry Reference: Methanediimine, n,n'-dicyclohexyl-(538-75-0)
• EPA Substance Registry System: Dicyclohexylcarbodiimide (538-75-0)

Description and Uses

Dicydohexyl carbodiimide is used in peptide chemistry as a coupling reagent. It is both an irritant and a sensitizer, and caused contact dermatitis in pharmacists and chemists.

dicyclohexylcarbodiimide is used as a dehydrating agent at room temperature after a short reaction time, after the reaction product is dicyclohexylurea. the product is very small solubility in an organic solvent, so that easy separation of the reaction product.

Safety

• Symbol(GHS): GHS05,GHS07,GHS08
• Signal word: Danger
• Hazard statements: H312-H315-H317-H318-H336-H351
• Precautionary statements: P202-P261-P280-P302+P352+P312-P305+P351+P338-P308+P313
• Hazard Codes: T,Xn,T+
• Risk Statements: 23/24/25-34-40-43-41-36/38-21-24-22-62-37/38-10-61-26-38-20/22
• Safety Statements: 26-36/37/39-45-41-24-37/39-24/25-36-16-53-28
• RIDADR: UN 2922 8/PG 2
• WGK Germany: 3
• RTECS: FF2160000
• F: 3-8-10-21
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: II
• HS Code: 29252000
• Hazardous Substances Data: 538-75-0(Hazardous Substances Data)
• Toxicity: LD50 orally in Rabbit: 1110 mg/kg LD50 dermal Rat 71 mg/kg
• Limited Quantities: 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)